1. Biologics, Biomaterial Synthesis and Characterisation Laboratories
Biological laboratories in GSBmE house extensive biochemistry and molecular biology, polymer synthesis and processing, biomaterials development and characterisation, cell culture (PC2), imaging (light, fluorescence & confocal) patch clamp and multichannel in vitro and in vivo electrophysiology, and animal housing/ surgical facilities. These laboratories are designed with multidisciplinary research in mind, allowing development of biomedical technologies from fundamental research to product design and testing.
RESEARCH AREAS: Bionics, Neural interfaces, Cell Technologies, Regenerative Medicine & Tissue Engineering, Biomaterials & Bioinspired Materials
Contact: Lynn Ferris
2. Electronics and Manufacturing Laboratories
Our Electronics and Manufacturing laboratories contain highly specialised equipment for prototyping, characterisation and validation of a range of implantable and non-implantable devices being researched in the school, prior to preclinical and biological testing. Facilities include but are not limited to laser welding and cutting, flip-chip bonding, ASIC design and testing, general dry electronics (PCB manufacture, soldering etc), specialised oscilloscopes, climate chamber testing, hermeticity testing, mini lathes, various microscopes and tools for manufacturing and a certified clean room.
RESEARCH AREAS: Medical & Surgical Robots, Bionics, Neural Interfaces, Telemonitoring, Advanced Manufacturing
Contact: Lynn Ferris
3. Imaging & Nanotechnology Laboratories
Cancer nanotechnology laboratories develop bespoke pharmacological agents and therapies. Fully equipped chemistry facilities allow us to synthesise tailored nanomaterials which are then characterised on-site and using UNSW facilities elsewhere. They are then tested in vitro in conventional and in three-dimensional cell cultures (on-site) by using confocal imaging and other methods. Animal testing occurs at the animal facility in UNSW.
Our tissue engineering laboratory produces engineered tissue-derived biomaterials for applications in the life sciences and medicine. We decellularize tissue which is then modified and repopulated with the cells of choice, or used as is for implantation, The equipment for tissue processing for tissue engineering applications includes research class optical microscopes, tissue culture and biomaterials engineering facilities. We also have capabilities for basic histopathological analysis.
Our advanced imaging laboratory develops new methods of biomolecular analysis at a single cell level that is quick, sensitive and accurate using customised fluorescence microscopy systems. We are applying this approach to understand biological systems, detect disease and monitor therapies in clinical settings. We characterise native colours and shapes of individual cells and tissues including in their most authentic in vivo setting. High content image analysis provides a metabolic “fingerprint” allowing to distinguish healthy from diseased cells. This approach has been applied to a number of health conditions including in ophthalmology, kidney disease and neurodegenerative diseases and work closely with medical partners in Australia and overseas to translate this technology to the clinic.
Similar approach is currently extended to medical images obtained in other modalities such as computed tomography (CT) and PET imaging.
RESEARCH AREAS: Advanced imaging, cancer nanotechnology
Contact: Ewa Goldys
4. Integrated Devices and Intelligent Diagnostics (ID2) Laboratory
The Integrated Devices and Intelligent Diagnostics (ID2) Laboratory accommodates advanced facilities for wet chemistry, DNA nanobiotechnology, electrochemical biosensing, microfluidic paper based analytical devices, stretchable biomaterials towards wearables and implants, intelligent nanoparticles, and signal cell analysis. ID2 laboratory is focusing on interdisciplinary and translational research with close end-user engagement by integrating chemistry, nanotechnology and biomedical engineering to solve the challenges with life science. ID2 lab targets to create a set of powerful toolkits to precisely quantify our health from point-of-care to in vivo monitoring with the impact on molecular diagnostics and biomedical engineering.
RESEARCH AREAS: Integrated Devices & Intelligent Diagnosis and Biosensing
Contact: Guozhen Liu
5. Molecular Surface Interaction Network Laboratory
The Molecular Surface Interaction Network laboratory houses a suite of instruments for the analysis of interactions between materials, molecules (protein, peptide, antibody, DNA, carbohydrate) and cells on the nanoscale.
Find out more here.
RESEARCH AREAS: Biomaterials and bio-inspired materials, cell technologies, Regenerative medicine and tissue engineering
Contact: Megan Lord
6. Associated Laboratories
2. Surgical & Orthopaedic Research Laboratories (Prince of Wales)